Struma ovarii has elicited considerable interest because of its many unique features since Ludwig Pick first elucidated its relationship to teratoma in the early part of the 20th century. 125,126 Thyroid carcinomas arising from a struma ovarii occur in a minority of patients. Malignant struma ovarii (MSO) includes tumor types seen in the eutopic thyroid, such as papillary thyroid carcinoma (both the classical type and the follicular variant) and follicular carcinoma. Thyroid-type carcinoma of struma ovarii. Scans were evaluated for the laterality, size, mass configuration, margins, internal architecture, presence of intracystic high attenuation lesions on precontrast scans, and cyst wall enhancement. Add Definition. Struma ovarii is a type of tumor of ovaries. After putting together clinical findings, special studies on tissues (if needed) and with microscope findings, the pathologist arrives at a definitive diagnosis. This type of tumor makes up only 1 percent of ovarian tumors.They develop into either a benign strumosis or a strumal carcinoid. Computed tomography (CT) scans of 13 pathologically proven struma ovarii were retrospectively reviewed by two radiologists in consensus. &NA; Since its first description in the early part of the twentieth century, struma ovarii has elicited considerable interest because of its many unique features; however, at present a number of aspects remain enigmatic. The most common thyroid-type malignancies to arise in struma ovarii are papillary and follicular carcinomas. Shaco-Levy, R., Peng, R. Y., Snyder, M. J., Osmond, G. W., Veras, E., Bean, S. M., ... & Robboy, S. J. Struma ovarii is a rare ovarian tumour that has been reported to represent 0.5%–1.0% of all ovarian tumours. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. The malignant nature of the other 10 tumors became apparent only after they recurred. A. Although the typical presentation is that of a pelvic mass, unusual clinical manifestations such as hyperthyroidism, ascites, and Meigs' syndrome have been recognised. In some cases, the tumor can release thyroid hormones resulting in associated complications, such as thyrotoxicosis, The treatment of Struma Ovarii involves surgery in most cases. Malignant struma ovarii: a population-level analysis of a large series of 68 patients. The prognosis of Struma Ovarii depends on whether the tumor is benign or malignant. Struma ovarii is a monodermal variant of ovarian teratoma, which was initially described by Bottlin in 1888 and, later, by Pick in 1902 and 1903, who recognized that struma ovarii was composed of thyroid tissue.1 Malignancy of struma ovarii is rare. click for more detailed meaning in Hindi, definition, pronunciation and example sentences. A struma ovarii (literally: goitre of the ovary) is a rare form of monodermal teratoma that contains mostly thyroid tissue, which may cause hyperthyroidism. Ovarian struma ovarii occurred in 12 (4.8%) of 251 cases of ovarian dermoid cysts. 1971, Keith Thomas, Religion and the Decline of Magic, Folio Society 2012, p. 186: This was the healing ritual for the King's Evil, the name given to scrofula or struma, the tubercular inflammation of the … It most commonly occurs as part of a teratoma, but may occasionally be encountered with serous or mucinous cystadenomas. The natural history of 27 cases of biologically malignant struma ovarii from a series of 88 cases of histologically malignant or histologically proliferative struma ovarii is described. Malignant teratomas may be additionally treated using chemotherapy and/or radiation therapy, In a majority, the prognosis of a benign teratoma is excellent with early appropriate treatment. We present a case of papillary thyroid carcinoma arising in a struma ovarii of the left ovary in a 21-year-old female. It was first discovered or elaborated in 1899. "Struma Ovarii" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Examination of the biopsy under a microscope by a pathologist is considered to be gold standard in arriving at a conclusive diagnosis, Biopsy specimens are studied initially using Hematoxylin and Eosin staining. Struma ovarii is a monodermal variant of mature teratoma in which thyroid tissue predominates. struma (countable and uncountable, plural strumas or strumae) Scrofula. A pathologist examines the biopsy under a microscope. Die Struma ovarii (lat. Struma (in Greek, Strimon), a river in Bulgaria and Greece. Struma ovarii is a rare ovarian tumor defined by the presence of thyroid tissue comprising more than 50% of the overall mass. Struma ovarii is a monodermal variant of ovarian teratoma, which was initially described by Bottlin in 1888 and, later, by Pick in 1902 and 1903, who recognized that struma ovarii was composed of thyroid tissue.1 Malignancy of struma ovarii is rare. It was first discovered or elaborated in 1899. In this tumor thyroid tissues are present w... Struma ovarii is a type of tumor of ovaries. Radiographic features . In general, most (small) tumors are asymptomatic and no significant symptoms are observed, while large tumors are known to present symptoms. It was first discovered or elaborated in 1899. Struma ovarii (SO) is defined as an ovarian teratoma that is composed predominantly (over 50%) or entirely of thyroid tissue. Write it here to share it with the entire community. © … 18 Beziehungen. &NA; Since its first description in the early part of the twentieth century, struma ovarii has elicited considerable interest because of its many unique features; however, at present a number of aspects remain enigmatic. (2013). Struma ovarii: role of imaging?. Abdominal imaging, 36(5), 627-631. 10 year old girl with tachycardia, normal thyroid and thyrotoxicosis with papillary thyroid carcinoma arising from a struma ovarii (Int J Surg Case Rep 2018;51:218) 48 year old woman with malignant struma ovarii presenting 14 years after oophorectomy and chemotherapy (Medicine (Baltimore) 2018;97:e13867) 52 year old woman with clinical features of … Definition. BACKGROUND: Malignant struma ovarii (MSO) is a germ cell tumor of the ovary histologically identical to differentiated thyroid cancers. [] 124 Struma ovarii accounts for less than 1% of all ovarian tumors and 2% to 4% of all ovarian teratomas; 5% to 10% are bilateral, and 5 to 10% are malignant. Struma ‚Drüsenschwellung am Hals‘, ‚Geschwulst‘) ist ein überwiegend einseitig auftretender, in der Regel gutartiger Tumor der Eierstöcke.Es handelt sich dabei um eine Variante des reifen Teratoms, die zu mehr als 50 Prozent aus reifem, regulär aufgebauten Schilddrüsengewebe besteht. CT and MR features of struma ovarii Takashi Ikeuchi,1 Takashi Koyama,2 Ken Tamai,3 Koji Fujimoto,2 Yoshiki Mikami,4 Ikuo Konishi,5 Kaori Togashi2 1Department of Radiology, Kansai Denryoku Hospital, 2-1-7 Fukushima Fukushima-ku Kawahara-cho, Osaka 553-0003, Japan 2Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, "Struma Ovarii" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Struma ovarii is a type of tumor of ovaries. 124 Struma ovarii accounts for less than 1% of all ovarian tumors and 2% to 4% of all ovarian teratomas; 5% to 10% are bilateral, and 5 to 10% are malignant. The vast majority of struma ovarii are benign tumours; however, malignant tumours of this type are found in a small percentage of cases. Thyroid tissue may demonstrate the same spectrum of pathological features as in the normal thyroid including benign and malignant changes. It is a typically benign tumor, but may transform into a malignancy, It is described as a form of monodermal teratoma of ovary. Exploration of the abdomen using laparotomy procedure is called ‘exploratory laparotomy’, Fine needle aspiration (FNA) biopsy of the tumor: A FNA biopsy may not be helpful, because one may not be able to visualize the different morphological areas of the tumor. INTRODUCTION. Malignant struma ovarii: a blinded study of 86 cases assessing which histologic features correlate with aggressive clinical behavior. Definition. Struma ovarii is a monodermal variant of ovarian teratoma, which was initially described by Bottlin in 1888 and, later, by Pick in 1902 and 1903, who recognized that struma ovarii was composed of thyroid tissue Göbös pajzsmirigy (struma nodosa) Szerző: Budai Endokrinközpont - Prof. Dr. … Struma ovarii occurred more frequently (68.8%) in the right adnexa and was seen with a normal CA‐125 level. Most patients were premenopausal, and the mean lesion diameter was 57.3 mm (range, 30‐95 mm). [from NCI] What does struma ovarii mean? [from NCI] Term Hierarchy. Latin, swelling of the lymph glands Approved by: Krish Tangella MD, MBA, FCAP. The purpose of this study was to evaluate computed tomographic findings of struma ovarii. a cushionlike swelling on an organ, as that at one side of the base of the capsule in many mosses. Ovarian struma ovarii occurred in 12 (4.8%) of 251 cases of ovarian dermoid cysts. The prognosis of these tumors is usually assessed on a case-by-case basis. Although the typical presentation is that of a pelvic mass, unusual clinical manifestations such as hyperthyroidism, ascites, and Meigs' syndrome have been recognised. It is defined by the presence of thyroid tissue comprising more than 50% of the overall mass. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis. History and Etymology for struma. Rarely, struma ovarii undergoes malignant transformation. All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. It is believed that abnormal differentiation of germ cells gives rise to the formation of this tumor. Mutations allow the cancer cells to grow and multiply uncontrollably to form new cancer cells, These tumors can invade nearby tissues and adjoining body organs, and even metastasize and spread to other regions of the body, Presence of a well-circumscribed tumor in the ovary; monodermal teratomas are generally benign, The tumors are cystic (fluid-filled) in nature, Generally, only one ovary is affected; but, involvement of both ovaries may be seen (bilateral teratoma), The tumors may range in size from a few cm to over 20 cm, Large tumors (size over 4 cm) can compress the surrounding structures or organs and give the sensation of an abdominal mass, Abdominal pain from large-sized ovarian tumors, Abdominal discomfort, heaviness, and tenderness (especially at the iliac fossa, which is an area near to the hip bone), Pelvic discomfort and pain; lower back pain, Frequent urination due to compression/pressure of the tumor, When metastasis is noted, it may result in weight loss, fatigue, and other systemic symptoms, Physical examination and complete medical history screening, Ultrasound scan of the pelvis: It is a non-invasive procedure that uses high frequency sound waves to produce real-time images, Transvaginal ultrasound: An ultrasound is inserted into the vagina and the mass is examined using sound waves, Abdominal and pelvic CT scan: It is a non-invasive procedure that provides more details of soft tissues, blood vessels, and internal organs, Pelvic MRI scan: It is a non-invasive medical test that uses a powerful magnetic field to produce images of soft tissues, bones, organs, and all other internal structures of the abdomen and pelvis, Hysteroscopy: This procedure involves placing a probe through the cervix to examine the cavity of the uterus, Laparoscopy: A special device is inserted through a small hole into the abdomen, to visually examine it. The extraovarian spread was evident at presentation in 17 patients. It is considered that it is the part of a teratoma. (2015). Shen, J., Xia, X., Lin, Y., Zhu, W., & Yuan, J. Meaning of struma ovarii. Knoten ist nicht gleich Krebs. (2011). struma ovarii The presence of mature thyroid tissue as the predominant tissue in an ovarian teratoma, which may cause clinical hyperthyroidism; 5-10% of struma ovarii become malignant, which is indicated by metastasis McGraw-Hill Concise Dictionary of Modern Medicine. Hence, a FNA biopsy as a diagnostic tool has certain limitations, and an open surgical biopsy is preferred, A tissue biopsy of the tumor is performed and sent to a laboratory for a pathological examination. The complications of Struma Ovarii may depend on whether the tumor is benign or malignant. ‘A 62-year-old white woman underwent right ovary resection that had a pathologic diagnosis of struma ovarii.’ ‘The case of a 38-year-old woman with malignant struma ovarii is described.’ ‘Aspiration biopsy cytology was performed for both strumae.’ First described by Von Klden in 1895 and Gottschalk in 1899, struma ovarii is the most common type of monodermal teratoma, and comprises about 3.0% of all ovarian teratomas. It is always important to discuss the effect of risk factors with your healthcare provider. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. A rare teratoid tumor of the ovary composed almost entirely of thyroid tissue, with large follicles containing abundant colloid. Dujardin, M. I., Sekhri, P., & Turnbull, L. W. (2014). Struma ovarii has elicited considerable interest because of its many unique features since Ludwig Pick first elucidated its relationship to teratoma in the early part of the 20th century. If necessary, a tissue sample is obtained for further analysis. Dictionary entry overview: What does struma mean? It is a typically benign … Patients may present with abdominal mass and unusual symptoms due to thyrotoxicosis, or with Meigs syndrome (ascites and pleural effusion). 5-10% of struma ovarii become malignant, the only absolute criterion for which is the presence of metastasis. 3 8, Hyperthyroidism is rare; however, the preoperative diagnosis of struma ovarii/malignant, Dictionary, Encyclopedia and Thesaurus - The Free Dictionary, the webmaster's page for free fun content, CYSTIC STRUMA OVARII: A RARE OVARIAN TERATOMA, Malignant struma ovarii: a blinded study of 86 cases assessing which histologic features correlate with aggressive clinical behavior, Study of histomorphological changes of teratomas in tertiary care hospital, structural maintenance of chromosomes (SMC) family, Strümpell-Leichtenstern encephalitis disease, Strumento Finanziario di Orientamento della Pesca. Also, presently, the risk factors for the same are not well-established, In many cases, no signs and symptoms of teratoma are observed and these tumors are diagnosed incidentally. Generally, the treatment of choice is complete surgical excision for all teratomas. Hence, measures to protect the individual’s fertility must be considered, before starting chemotherapy, Damage to the muscles, vital nerves, and blood vessels, during surgery, Post-surgical infection at the wound site is a potential complication. The cause of formation of the tumor is unknown. The most common thyroid-type malignancies to arise in struma ovarii are papillary and follicular carcinomas. Archives of pathology & laboratory medicine, 136(2), 172-178. A river, about 415 km (260 mi) long, of western Bulgaria and northeast Greece flowing southward to an inlet of the Aegean Sea. Occasionally there are symptoms of hyperthyroidism. Adverts are the main source of Revenue for DoveMed. 5-10% of struma ovarii become malignant, the only absolute criterion for which is the presence of metastasis. The malignant nature of the other 10 tumors became apparent only after they recurred. The incidence of malignancy arising in patients with struma ovarii is rare. There is a paucity of data on this neoplasm, with fewer than 200 reported cases. Struma Ovarii (n.). It is important to note that having a risk factor does not mean that one will get the condition. (1-6) It is defined as an ovarian teratoma that is composed predominantly of thyroid tissue (> 50%), or forms a … A tumor consisting of different types of tissue, as of skin, hair, and muscle, caused by the development of independent germ cells. struma ova´rii a teratoid ovarian tumor composed of thyroid tissue. Die häufigste Ursache einer Struma ist … Some risk factors are more important than others. The Journal of Clinical Endocrinology & Metabolism, 98(12), 4599-4605. Struma ovarii is a rare ovarian tumor that was first described in 1899. 1. abnormally enlarged thyroid gland; can result from underproduction or overproduction of hormone or from a deficiency of iodine in the diet 2. a form of tuberculosis characterized by swellings of the lymphatic glands Familiarity information: STRUMA used as a noun is rare. 5-10% of struma ovarii become malignant, the only absolute criterion for which is the presence of metastasis. . Binti Md Nor, N., Kusumoto, T., Inoue, S., Nakamura, K., Seki, N., Hongo, A., ... & Hiramatsu, Y. [] Although 5–15% of all ovarian teratomas may contain some thyroid tissue; only 2% of these are made exclusively of SO. Botany. Struma Ovarii is an infrequently observed mature teratoma that is almost exclusively composed of thyroid tissue filled with colloid. The extraovarian spread was evident at presentation in 17 patients. A rare teratoid tumor of the ovary composed almost entirely of thyroid tissue, with large follicles containing abundant colloidOccasionally there are symptoms of hyperthyroidism. It is a typically benign tumor, but may transform into a malignancy. Struma ovarii is a rare entity consisting of thyroid components that are part of a teratoma or dermoid in the ovary. Struma ovarii or monodermal teratoma is a specialized ovarian neoplasm which mainly constitutes mature thyroid tissue. Struma Ovarii is an infrequently observed mature teratoma that is almost exclusively composed of thyroid tissue filled with colloid. struma ovarii in Hindi :: स्ट्रूमा ओवेरियाइ…. Ovary tumor - Struma ovarii. Exploration of the abdomen using a laparoscope is called ‘exploratory laparoscopy’, Laparotomy: The abdomen is opened through an incision for examination, and if required, a biopsy sample obtained. Struma Ovarii (n.). Struma ovarii definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. [ 18 ] Read More The aberrant thyroid tissue shows morphologic changes identical to thyroid adenoma or carcinoma. The gross pathologic appearance of struma ovarii differs from that of mature cystic teratomas where struma ovarii consist of amber-colored thyroid tissue, with hemorrhage, necrosis, and fibrosis. 1. "Struma" steht dabei für die große Schilddrüse, "nodosa" für die Knoten. An ovarian mature teratoma characterized by the presence of aberrant thyroid tissue with morphologic changes identical to thyroid carcinoma. (2012). In Untersuchungsbefunden liest man manchmal auch noch weitere Differenzierungen wie "uninodosa" (nur ein Knoten) oder "multinodosa" (mehrere Knoten). Struma ovarii Definition, Meaning, Symptoms, Causes, Treatment Diseases. Diagnosis of Struma ovarii with medical imaging. Strimón, river, 216 mi (348 km) long, rising in the mountains of W Bulgaria and flowing S, through NE Greece, to the Aegean Sea. Rarely, papillary carcinoma of thyroid can arise in Struma Ovarii, Metastasis of malignant tumors to distant sites, Recurrence of the tumor following its incomplete surgical removal, Side effects of radiation therapy that may include sunburn-like rashes, where radiation was targeted, red or dry skin, heaviness of the breasts, and general fatigue, Side effects of chemotherapy, which may include nausea, vomiting, hair loss, decreased appetite, mouth sores, fatigue, low blood cell counts, and a higher chance of developing infections, The treatment can also cause infertility in men and women. Most patients were premenopausal, and the mean lesion diameter was 57.3 mm (range, 30‐95 mm). Acta Medica Okayama, 67(3), 191-195. Struma Ovarii Struma ovarii Engelsk definition. © 2003 by Saunders, an imprint of Elsevier, Inc. METHODS: Computed tomography (CT) scans of 13 pathologically proven struma ovarii were retrospectively reviewed by two radiologists in consensus. (1) First described by Von Klden in 1895 and Gottschalk in 1899, struma ovarii is the most common type of monodermal teratoma, and comprises about 3.0% of all ovarian teratomas. Have a definition for Struma ovarii ? Struma ovarii is a variant of a germ cell tumor composed predominantly of thyroid tissue. A rare ovarian tumor, regarded as teratomatous, in which thyroid tissue has surpassed the other elements; occasionally associated with hyperthyroidism. Look it up now! Struma ‚Drüsenschwellung am Hals‘, ‚Geschwulst‘) ist ein überwiegend einseitig auftretender, in der Regel gutartiger Tumor der Eierstöcke. Many clinical conditions may have similar signs and symptoms. The signs and symptoms of Struma Ovarii may vary from one individual to another. However, the prognosis of a malignant Struma Ovarii depends upon numerous factors and can be only assessed on a case-by-case basis, Struma Ovarii is a rare type of teratoma that may be observed in women over 40 years of age, including in postmenopausal women, No specific racial or ethnic group predilection is noted, Nearly, 3% of all mature teratomas are reported to be Struma Ovarii tumors, Currently, no definite risk factors have been identified for Struma Ovarii, In general, it is known that cancers form when normal, healthy cells begin transforming into abnormal cells - these cancer cells grow and divide uncontrollably (and lose their ability to die), resulting in the formation of a mass or a tumor, The transformation of normally healthy cells into cancerous cells may be the result of genetic mutations. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. [] It may demonstrate pathologic features that can be seen in the normal thyroid including benign and malignant changes. "Struma Ovarii" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Definition of struma ovarii in the Definitions.net dictionary. Coexistence of malignant struma ovarii and cervical papillary thyroid carcinoma. It was found that 6% a rare form of ovarian tumor. Some tumors may grow to large sizes and cause obstructive signs and symptoms. The following surgical procedures may be considered: Cystectomy or surgical removal of the ovarian cyst, Oophorectomy or removal of the affected ovary, Additionally, chemotherapy and/or radiation therapy may be necessary for malignant tumors, Follow-up care with regular screening and check-ups are important and encouraged, Tumors that behave in a benign manner, with complete surgical removal of the tumor, can have an excellent prognosis, Malignant teratomas may be aggressive, difficult to treat (complete tumor resection may not be possible), and can spread to other sites. Please remove adblock to help us create the best medical content found on the Internet. Struma ovarii associated with pseudo-Meigs' syndrome and elevated serum CA 125: a case report and review of the literature. ‘The most common forms of this variant are struma ovarii and carcinoid in the ovary.’ More example sentences ‘A 62-year-old white woman underwent right ovary resection that had a pathologic diagnosis of struma ovarii.’ 1. Teratoma of ovary is a rare type of ovarian tumor that arises from the germ cells, which is usually observed in adolescent and young women, Struma Ovarii is mostly observed in middle-aged and older women. To qualify as a struma ovarii tumors more than 50% of the tumor should be composed of thyroid tissue 7. Struma ovarii is a rare ovarian tumour that has been reported to represent 0.5%–1.0% of all ovarian tumours. Riedel's struma Riedel's thyroiditis. Struma ovarii comprises 1–4% of all dermoid tumors of the ovary, and very rarely presents in a malignant form, occurring in 0.3%–5% of all struma ovarii tumors [2–4]. 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